FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations
![IJMS | Free Full-Text | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations IJMS | Free Full-Text | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations](https://www.mdpi.com/ijms/ijms-24-01342/article_deploy/html/images/ijms-24-01342-g001.png)
IJMS | Free Full-Text | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations
![MDM2 amplification by FISH performed on the same core needle biopsy... | Download Scientific Diagram MDM2 amplification by FISH performed on the same core needle biopsy... | Download Scientific Diagram](https://www.researchgate.net/publication/44623654/figure/fig4/AS:277292690493443@1443123137113/MDM2-amplification-by-FISH-performed-on-the-same-core-needle-biopsy-from-the-liposarcoma.png)
MDM2 amplification by FISH performed on the same core needle biopsy... | Download Scientific Diagram
Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma | PLOS ONE
![A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans: Cell A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans: Cell](https://www.cell.com/cms/attachment/d80dd325-c692-4565-9781-4837f8b18c66/gr1_lrg.jpg)
A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans: Cell
![FISH to detect the MDM2 gene copy number in MM. Dual color FISH study... | Download Scientific Diagram FISH to detect the MDM2 gene copy number in MM. Dual color FISH study... | Download Scientific Diagram](https://www.researchgate.net/publication/10761973/figure/fig2/AS:601735584284683@1520476351903/FISH-to-detect-the-MDM2-gene-copy-number-in-MM-Dual-color-FISH-study-shows-A-a-case.png)
FISH to detect the MDM2 gene copy number in MM. Dual color FISH study... | Download Scientific Diagram
![mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease - Wege - 2022 - International Journal of Cancer - Wiley Online Library mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease - Wege - 2022 - International Journal of Cancer - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/92f0b4b3-11b7-44b0-b2cc-9dfe3813b9ce/ijc33911-toc-0001-m.jpg)
mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease - Wege - 2022 - International Journal of Cancer - Wiley Online Library
![Analysis of MDM2 Amplification: Next-Generation Sequencing of Patients With Diverse Malignancies | JCO Precision Oncology Analysis of MDM2 Amplification: Next-Generation Sequencing of Patients With Diverse Malignancies | JCO Precision Oncology](https://ascopubs.org/na101/home/literatum/publisher/asco/journals/content/po/2018/po.2018.2/po.17.00235/20180712/images/large/po.17.00235t1.jpeg)
Analysis of MDM2 Amplification: Next-Generation Sequencing of Patients With Diverse Malignancies | JCO Precision Oncology
![Cancers | Free Full-Text | MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma Cancers | Free Full-Text | MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma](https://pub.mdpi-res.com/cancers/cancers-12-00540/article_deploy/html/images/cancers-12-00540-g003.png?1585799861)
Cancers | Free Full-Text | MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma
![Frontiers | Targeting Mouse Double Minute 2: Current Concepts in DNA Damage Repair and Therapeutic Approaches in Cancer Frontiers | Targeting Mouse Double Minute 2: Current Concepts in DNA Damage Repair and Therapeutic Approaches in Cancer](https://www.frontiersin.org/files/Articles/537486/fphar-11-00631-HTML/image_m/fphar-11-00631-g001.jpg)
Frontiers | Targeting Mouse Double Minute 2: Current Concepts in DNA Damage Repair and Therapeutic Approaches in Cancer
![IJMS | Free Full-Text | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations IJMS | Free Full-Text | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations](https://pub.mdpi-res.com/ijms/ijms-24-01342/article_deploy/html/images/ijms-24-01342-g002.png?1673344601)
IJMS | Free Full-Text | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations
Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma | PLOS ONE
![Amplification of the MDM2 gene in a well-differentiated liposarcoma... | Download Scientific Diagram Amplification of the MDM2 gene in a well-differentiated liposarcoma... | Download Scientific Diagram](https://www.researchgate.net/publication/272840106/figure/fig1/AS:272536294391834@1441989124626/Amplification-of-the-MDM2-gene-in-a-well-differentiated-liposarcoma-fluorescence-in-situ.png)
Amplification of the MDM2 gene in a well-differentiated liposarcoma... | Download Scientific Diagram
![Bellvitge Pathology on Twitter: "This case was signed out as Dedifferentiated liposarcoma. MDM2 amplification was detected on FISH, both in the well differentiated areas and in the myxoid ones. A few bullet Bellvitge Pathology on Twitter: "This case was signed out as Dedifferentiated liposarcoma. MDM2 amplification was detected on FISH, both in the well differentiated areas and in the myxoid ones. A few bullet](https://pbs.twimg.com/media/EP_po3qW4AEUUbl.jpg:large)
Bellvitge Pathology on Twitter: "This case was signed out as Dedifferentiated liposarcoma. MDM2 amplification was detected on FISH, both in the well differentiated areas and in the myxoid ones. A few bullet
![Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms | Modern Pathology Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms | Modern Pathology](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fmodpathol.2008.84/MediaObjects/41379_2008_Article_BFmodpathol200884_Fig1_HTML.jpg)